KMID : 0828520080120040251
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Journal of the Korean Geriatrics Society 2008 Volume.12 No. 4 p.251 ~ p.254
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Successful Treatment of Thrombotic Thrombocytopenic Purpura with Recurrent Transient Ischemic Attacks in Old Age
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Ku Bon-D.
Kim Hye-Yun
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Abstract
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Thrombotic thrombocytopenic purpura (TTP) is an uncommon fatal disorder of young adults characterized by thrombocytopenia, microangiopathic hemolytic anem ia, fluctuating neurologic dysfunction, fever, and renal dysfunction. The fluctuating neurologic dysfunction, which is mainly due to small arteriolar or capillary ischemic vasculopathy, suggests impending stroke. We report a 72-year-old woman who has had recurrent and progressive transient ischemic attacks and confusion after a large amount of bloodletting. She recovered completely after intensive plasmapheresis and immunosuppressant treatment. This case illustrates that aggressive treatment, even in old age, may prevent permanent neurologic deficits when stroke is impending and com plicated by TTP.
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KEYWORD
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Thrombocytopenic thrombotic purpura, Transient ischemic attack, Plasmapheresis
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